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Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 368-373 doi: 10.1007/s11684-015-0403-1

Abstract: /reperfusion (I/R) injury in pulmonary, intestinal, and myocardial tissue.We investigated the potential role of GLP-2 pretreatment on hepatic I/R injury in rats.The first group was the control group; the second group was the vehicle-treated hepatic ischemia/reperfusionA portal triad was created to induce ischemia with a vascular atraumatic clamp.After 40 min, the clamp was released to initiate hepatic reperfusion for 6 h.

Keywords： ischemia/reperfusion     liver     glucagon-like peptide-2     alanine aminotransferase    

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Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 317-322 doi: 10.1007/s11684-010-0035-4

Abstract: The inhibitory effect of different reperfusion periods 45 min following hepatic ischemia on the expressionrandomly divided into four groups: normal control group (CO group), sham-operated group (SO group), ischemiarat model of I/R was established by using a non-invasive artery clamp to clip (45 min) or relax the hepaticIt is suggested that the digestive tract congestion injury caused by liver ischemia can upregulate theexpression of CCK and VIP in the jejunum following reperfusion.

Keywords： hepatic ischemia-reperfusion     digestive tract congestion     cholecystokinin     vasoactive intestinal peptide    

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Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 433-437 doi: 10.1007/s11684-007-0085-4

Abstract: The effect of peripherally administered oxytocin (OT) on gastric ischemia-reperfusion injury (GI-RI)The animal GI-RI model was established by clamping the celiac artery for 30 min to induce ischemia andthen released to allow reperfusion for 1 h, and the degree of GI-RI was assessed by scoring the gastricresults indicated that the oxytocin could significantly protect gastric mucosal against injury induced by ischemia-reperfusion

Keywords： control     significant difference     surgical     statistical significance     Sprague-Dawley    

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The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 329-331 doi: 10.1007/s11684-012-0211-9

Abstract: ow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusionthe allograft renal vein was twisted because of the surgeon’s mistake, which caused the warm ischemiaof allograft after reperfusion.The allograft restored blood flow without second reperfusion and cold preservation after 9 min of warmischemia.

Keywords： renal transplantation     vein twist     ischemia-reperfusion injury    

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Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 87-92 doi: 10.1007/s11684-007-0017-3

Abstract: The aim of this paper is to explore the effect of intestinal ischemia/reperfusion (I/R) injury on leptinintestinal I/R injury model of rats was made; the rats were grouped according to the time of after 60 min ischemiaCompared with the levels before the injury, serum leptin in 60 min ischemia/30 min reperfusion (I60´R30

Keywords： significant difference     intestinal I/R     transcriptase-polymerase     metabolic     central secretory    

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The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 391-395 doi: 10.1007/s11684-008-0075-1

Abstract: brains of Kunming mice, six-month-old mice ( = 72) were pretreated with heat stress and subsequent ischemia/reperfusion by clipping of their bilateral cervical common arteries for 7 min.randomly divided into four groups: (1) normal control group; (2) heat stress pretreatment followed by ischemiaand reperfusion group (HS/IR); (3) ischemia and reperfusion group (IR); (4) heat stress group (HS).

Keywords： calcitonin gene-related     subsequent ischemia/reperfusion     computer     cerebrum     CGRP excretion    

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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract: barrier destruction is widely observed among patients receiving liver transplant and suffering from ischemia–reperfusion or rejection injuries because of the relationship between the intestine and the liver

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic post-conditioning

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 301-305 doi: 10.1007/s11684-013-0283-1

Abstract:

Systemic inflammatory response following myocardial ischemia-reperfusion injury (IRI) to a specific

Keywords： adiponectin     ischemic post-conditioning     ischemia reperfusion injury     diabetes    

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Metformin and metabolic diseases: a focus on hepatic aspects

Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 173-186 doi: 10.1007/s11684-015-0384-0

Abstract: As a drug that primarily targets the liver, metformin suppresses hepatic glucose production (HGP), servingAs supported by the results from both human and animal studies, metformin improves hepatic steatosisMechanistically, the beneficial effects of metformin on hepatic aspects are mediated through both adenosine

Keywords： metformin     diabetes     hepatic steatosis     inflammatory response     insulin resistance    

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Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma: a

Li Ma, Bin Wang, Yuanxiong Long, Hanmin Li

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 191-202 doi: 10.1007/s11684-017-0512-0

Abstract:

Primary hepatic carcinoma (PHC) is a common malignant tumor in China.review with meta-analysis aimed to assess the effect of TCM combined with Western therapy on primary hepatic

Keywords： traditional Chinese medicine     primary hepatic carcinoma     meta-analysis    

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Urotensin II receptor antagonist reduces hepatic resistance and portal pressure through enhanced eNOS-dependent

Ruoxi Zhang, Jing Chen, Diangang Liu, Yu Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 398-408 doi: 10.1007/s11684-019-0689-5

Abstract: receptor (UT) antagonist palosuran on rats with carbon tetrachloride (CCl )-induced cirrhosis, the hepaticfibrosis, the metalloproteinase-13 (MMP-13)/ tissue inhibitor of metalloproteinase-1 (TIMP-1) ratio, hepaticPrimary hepatic stellate cells (HSCs) are used to investigate the changes in UII/UT expression and thethat long-term administration of palosuran can decrease PP in cirrhosis, which results from decreased hepatic

Keywords： portal hypertension     cirrhosis     urotensin II     palosuran     hepatic stellate cell    

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Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 197-205 doi: 10.15302/J-FASE-2018245

Abstract: activity of rats in an open-field test, which was associated with attenuated neuronal damage induced by ischemiaserum SOD activity was significantly greater, MDA level lower in the leonurine group as compared with ischemiaTaken together, our results demonstrated that leonurine attenuated brain injury during ischemia via antioxidative

Keywords： cerebral ischemia     GABA     neuroprotection     leonurine     SOD    

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Beneficial effects of preventive cholecystectomy in patients with hepatic cancer

LIU Anzhong, LI Jun, HUA Huwei

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 139-142 doi: 10.1007/s11684-008-0026-x

Abstract: is no conclusive answer to the question whether excising gall bladder is helpful to the patient with hepaticThe survival rate of patients with hepatic cancer for more than two years has been increased, and thestone are relatively higher among these patients, which may seriously complicate treatment of advanced hepaticfrom 2002 to 2006 to assess the clinical significance of preventive cholecystectomy in patients with hepaticOne hundred and eighteen cases of postoperative patients with hepatic cancer, who survived for more than
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Paeoniflorin prevents hepatic fibrosis of by inhibiting TGF-β1 production from macrophages in mice

CHU Deyong, LI Conglei, SHEN Jilong, WU Qiang

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 154-165 doi: 10.1007/s11684-008-0029-7

Abstract: In order to investigate the effect of paeoniflorin (PAE) on hepatic fibrosis of mice with and , a modelof hepatic fibrosis caused by schistosomiasis was established in mice infected with cercariae of .Hepatic granuloma and fibrosis were evaluated via HE and Masson staining. The expression of ?1 in optimum macrophage-conditioned medium (OPMCM) on the proliferation of hepatic stellate cells (HSCsIn a word, PAE can prevent hepatic granuloma and fibrosis caused by schistosomiasis japonica through

Keywords： cercariae     collagen     hyaluronic     OPMCM     soluble    

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Influence of β-elemene on the secretion of angiotensin II and expression of AT1R in hepatic stellate

Ling YANG, Rui ZHU, Qingjing ZHU, Dan DAN, Jin YE, Keshu XU, Xiaohua HOU

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 36-40 doi: 10.1007/s11684-009-0020-y

Abstract: the secretion of angiotensin II (ANG II) and the expression of angiotensin receptor type 1 (AT1R) in hepaticprotein expression of AT1R, which may be the mechanism by which β-elemene prevents the progress of hepatic

Keywords： liver cirrhosis     beta-elemene     hepatic stellate cells     angiotensin II     receptor     angiotensin     type 1    

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Title Author Date Type Operation

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Journal Article

Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Journal Article

Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Journal Article

The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Journal Article

Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Journal Article

The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic post-conditioning

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Journal Article

Metformin and metabolic diseases: a focus on hepatic aspects

Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu

Journal Article

Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma: a

Li Ma, Bin Wang, Yuanxiong Long, Hanmin Li

Journal Article

Urotensin II receptor antagonist reduces hepatic resistance and portal pressure through enhanced eNOS-dependent

Ruoxi Zhang, Jing Chen, Diangang Liu, Yu Wang

Journal Article

Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Journal Article

Beneficial effects of preventive cholecystectomy in patients with hepatic cancer

LIU Anzhong, LI Jun, HUA Huwei

Journal Article

Paeoniflorin prevents hepatic fibrosis of by inhibiting TGF-β1 production from macrophages in mice

CHU Deyong, LI Conglei, SHEN Jilong, WU Qiang

Journal Article

Influence of β-elemene on the secretion of angiotensin II and expression of AT1R in hepatic stellate

Ling YANG, Rui ZHU, Qingjing ZHU, Dan DAN, Jin YE, Keshu XU, Xiaohua HOU

Journal Article